The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver

The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver

The ABC transporter ABCG1 (ATP binding cassette transporter G1), expressed in macrophages, liver, and other tissues, has been implicated in the efflux of cholesterol to high density lipoprotein. The ABCG1 gene is transcriptionally activated by cholesterol loading and activators of liver X receptors...

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Bibliographic Details
Main Authors: Steven L. Sabol, H. Bryan Brewer, Jr., Silvia Santamarina-Fojo
Format: Article
Language:English
Published: Elsevier 2005-10-01
Series:Journal of Lipid Research
Subjects:
ATP binding cassette transporter
liver X receptor
retinoid X receptor
cholesterol
hepatocyte
oxysterols
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520329060

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