Evidence for the Effect of Vaccination on Host-Pathogen Interactions in a Murine Model of Pulmonary Tuberculosis by Mycobacterium tuberculosis

Evidence for the Effect of Vaccination on Host-Pathogen Interactions in a Murine Model of Pulmonary Tuberculosis by Mycobacterium tuberculosis

The global control of Tuberculosis remains elusive, and Bacillus Calmette-Guérin (BCG) -the most widely used vaccine in history—has proven insufficient for reversing this epidemic. Several authors have suggested that the mass presence of vaccinated hosts might have affected the Mycobacterium tubercu...

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Bibliographic Details
Main Authors: Zyanya Lucia Zatarain-Barrón, Octavio Ramos-Espinosa, Brenda Marquina-Castillo, Jorge Barrios-Payán, Fernanda Cornejo-Granados, Otoniel Maya-Lucas, Gamaliel López-Leal, Camilo Molina-Romero, Richard M. Anthony, Adrián Ochoa-Leyva, Inti Alberto De La Rosa-Velázquez, Rosa Gloria Rebollar-Vega, Robin M. Warren, Dulce Adriana Mata-Espinosa, Rogelio Hernández-Pando, Dick van Soolingen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
BCG vaccination
Beijing genotype
virulence
lung transcriptome
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00930/full

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