A phylogenetic method to perform genome-wide association studies in microbes that accounts for population structure and recombination.
Genome-Wide Association Studies (GWAS) in microbial organisms have the potential to vastly improve the way we understand, manage, and treat infectious diseases. Yet, microbial GWAS methods established thus far remain insufficiently able to capitalise on the growing wealth of bacterial and viral gene...
Main Authors: | Caitlin Collins, Xavier Didelot |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-02-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1005958 |
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