Combining IL-2-based immunotherapy with commensal probiotics produces enhanced antitumor immune response and tumor clearance
Background Interleukin-2 (IL-2) serves as a pioneer of immunotherapeutic agent in cancer treatment. However, there is a considerable proportion of patients who cannot benefit from this therapy due to the limited clinical responses and dose-limiting toxicities. Mounting evidence indicates that commen...
Main Authors: | Linlin Shi, Jianyong Sheng, Guozhong Chen, Changping Shi, Chaiwoo Park, Bixiang Zhang, Xiangliang Yang |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2020-07-01
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Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/8/2/e000973.full |
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