Mapping the Lineage Relationship between CXCR5+ and CXCR5− CD4+ T Cells in HIV-Infected Human Lymph Nodes

Mapping the Lineage Relationship between CXCR5+ and CXCR5− CD4+ T Cells in HIV-Infected Human Lymph Nodes

Summary: CXCR5 is a key marker of follicular helper T (TFH) cells. Using primary lymph nodes (LNs) from HIV-infected patients, we identified a population of CXCR5− CD4+ T cells with TFH-cell-like features. This CXCR5− subset becomes expanded in severe HIV infection and is characterized by the upregu...

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Bibliographic Details
Main Authors: Daniel Del Alcazar, Yifeng Wang, Chenfeng He, Ben S. Wendel, Perla M. Del Río-Estrada, Jerome Lin, Yuria Ablanedo-Terrazas, Michael J. Malone, Stefany M. Hernandez, Ian Frank, Ali Naji, Gustavo Reyes-Terán, Ning Jiang, Laura F. Su
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719310770

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