Exposure Setup and Dosimetry for a Study on Effects of Mobile Communication Signals on Human Hematopoietic Stem Cells in vitro

In this paper we describe the design of an exposure setup used to study possible non-thermal effects due to the exposure of human hematopoietic stem cells to GSM, UMTS and LTE mobile communication signals. The experiments are performed under fully blinded conditions in a TEM waveguide located in...

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Main Authors: M. Rohland, K. Baaske, K. Gläser, H. Hintzsche, H. Stopper, T. Kleine-Ostmann, T. Schrader
Format: Article
Language:deu
Published: Copernicus Publications 2017-09-01
Series:Advances in Radio Science
Online Access:https://www.adv-radio-sci.net/15/207/2017/ars-15-207-2017.pdf
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spelling doaj-0d91a67cfed444ada220ef08f67ea3512020-11-24T21:07:34ZdeuCopernicus PublicationsAdvances in Radio Science 1684-99651684-99732017-09-011520721310.5194/ars-15-207-2017Exposure Setup and Dosimetry for a Study on Effects of Mobile Communication Signals on Human Hematopoietic Stem Cells in vitroM. Rohland0K. Baaske1K. Gläser2H. Hintzsche3H. Hintzsche4H. Stopper5T. Kleine-Ostmann6T. Schrader7Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, GermanyPhysikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, GermanyInstitut für Pharmakologie und Toxikologie, Universität Würzburg, Versbacher Str. 9, 97078 Würzburg, GermanyInstitut für Pharmakologie und Toxikologie, Universität Würzburg, Versbacher Str. 9, 97078 Würzburg, Germanypresent address: Bavarian Health and Food Safety Authority, Eggenreuther Weg 43, 91058 Erlangen, GermanyInstitut für Pharmakologie und Toxikologie, Universität Würzburg, Versbacher Str. 9, 97078 Würzburg, GermanyPhysikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, GermanyPhysikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig, GermanyIn this paper we describe the design of an exposure setup used to study possible non-thermal effects due to the exposure of human hematopoietic stem cells to GSM, UMTS and LTE mobile communication signals. The experiments are performed under fully blinded conditions in a TEM waveguide located inside an incubator to achieve defined environmental conditions as required for the living cells. Chamber slides containing the cells in culture medium are placed on the septum of the waveguide. The environmental and exposure parameters such as signal power, temperatures, relative humidity and CO<sub>2</sub> content of the surrounding atmosphere are monitored permanently during the exposure experiment. The power of the exposure signals required to achieve specific absorption rates of 0.5, 1, 2 and 4 W kg<sup>−1</sup> are determined by numerical calculation of the field distribution inside the cell culture medium at 900 MHz (GSM), 1950 MHz (UMTS) and 2535 MHz (LTE). The dosimetry is verified both with scattering parameter measurements on the waveguide with and without containers filled with cell culture medium and with temperature measurements with non-metallic probes in separate heating experiments.https://www.adv-radio-sci.net/15/207/2017/ars-15-207-2017.pdf
collection DOAJ
language deu
format Article
sources DOAJ
author M. Rohland
K. Baaske
K. Gläser
H. Hintzsche
H. Hintzsche
H. Stopper
T. Kleine-Ostmann
T. Schrader
spellingShingle M. Rohland
K. Baaske
K. Gläser
H. Hintzsche
H. Hintzsche
H. Stopper
T. Kleine-Ostmann
T. Schrader
Exposure Setup and Dosimetry for a Study on Effects of Mobile Communication Signals on Human Hematopoietic Stem Cells in vitro
Advances in Radio Science
author_facet M. Rohland
K. Baaske
K. Gläser
H. Hintzsche
H. Hintzsche
H. Stopper
T. Kleine-Ostmann
T. Schrader
author_sort M. Rohland
title Exposure Setup and Dosimetry for a Study on Effects of Mobile Communication Signals on Human Hematopoietic Stem Cells in vitro
title_short Exposure Setup and Dosimetry for a Study on Effects of Mobile Communication Signals on Human Hematopoietic Stem Cells in vitro
title_full Exposure Setup and Dosimetry for a Study on Effects of Mobile Communication Signals on Human Hematopoietic Stem Cells in vitro
title_fullStr Exposure Setup and Dosimetry for a Study on Effects of Mobile Communication Signals on Human Hematopoietic Stem Cells in vitro
title_full_unstemmed Exposure Setup and Dosimetry for a Study on Effects of Mobile Communication Signals on Human Hematopoietic Stem Cells in vitro
title_sort exposure setup and dosimetry for a study on effects of mobile communication signals on human hematopoietic stem cells in vitro
publisher Copernicus Publications
series Advances in Radio Science
issn 1684-9965
1684-9973
publishDate 2017-09-01
description In this paper we describe the design of an exposure setup used to study possible non-thermal effects due to the exposure of human hematopoietic stem cells to GSM, UMTS and LTE mobile communication signals. The experiments are performed under fully blinded conditions in a TEM waveguide located inside an incubator to achieve defined environmental conditions as required for the living cells. Chamber slides containing the cells in culture medium are placed on the septum of the waveguide. The environmental and exposure parameters such as signal power, temperatures, relative humidity and CO<sub>2</sub> content of the surrounding atmosphere are monitored permanently during the exposure experiment. The power of the exposure signals required to achieve specific absorption rates of 0.5, 1, 2 and 4 W kg<sup>−1</sup> are determined by numerical calculation of the field distribution inside the cell culture medium at 900 MHz (GSM), 1950 MHz (UMTS) and 2535 MHz (LTE). The dosimetry is verified both with scattering parameter measurements on the waveguide with and without containers filled with cell culture medium and with temperature measurements with non-metallic probes in separate heating experiments.
url https://www.adv-radio-sci.net/15/207/2017/ars-15-207-2017.pdf
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