131I-Traced PLGA-Lipid Nanoparticles as Drug Delivery Carriers for the Targeted Chemotherapeutic Treatment of Melanoma

131I-Traced PLGA-Lipid Nanoparticles as Drug Delivery Carriers for the Targeted Chemotherapeutic Treatment of Melanoma

Abstract Herein, folic acid (FA) conjugated Poly(d,l-lactide-co-glycolide) (PLGA)-lipid composites (FA-PL) were developed as nanocarriers for the targeted delivery of insoluble anti-cancer drug paclitaxel (PTX), resulting FA-PLP nanoparticles. Furthermore, 131I, as a radioactive tracer, was used to...

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Bibliographic Details
Main Authors: Haiyan Wang, Weizhong Sheng
Format: Article
Language:English
Published: SpringerOpen 2017-05-01
Series:Nanoscale Research Letters
Subjects:
Nanocarrier
PLGA-lipid
131I
Biodistribution
Drug delivery
Melanoma
Online Access:http://link.springer.com/article/10.1186/s11671-017-2140-7

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http://link.springer.com/article/10.1186/s11671-017-2140-7

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