Early goal-directed therapy using a physiological holistic view: the ANDROMEDA-SHOCK—a randomized controlled trial

Abstract Background Septic shock is a highly lethal condition. Early recognition of tissue hypoperfusion and its reversion are key factors for limiting progression to multiple organ dysfunction and death. Lactate-targeted resuscitation is the gold-standard under current guidelines, although it has s...

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Bibliographic Details
Main Authors: Glenn Hernández, Alexandre Biasi Cavalcanti, Gustavo Ospina-Tascón, Fernando Godinho Zampieri, Arnaldo Dubin, F. Javier Hurtado, Gilberto Friedman, Ricardo Castro, Leyla Alegría, Maurizio Cecconi, Jean-Louis Teboul, Jan Bakker, The ANDROMEDA-SHOCK Study Investigators
Format: Article
Language:English
Published: SpringerOpen 2018-04-01
Series:Annals of Intensive Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13613-018-0398-2