Actin-microtubule interplay coordinates spindle assembly in human oocytes

Actin and microtubules contribute to successful oocyte maturation, but if and how these two networks communicate in human oocytes is unclear. Here the authors show that actin-microtubule interactions are essential for correct segregation of human nuclear genomic content.

Bibliographic Details
Main Authors: Johannes Roeles, Georgios Tsiavaliaris
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12674-9
Description
Summary:Actin and microtubules contribute to successful oocyte maturation, but if and how these two networks communicate in human oocytes is unclear. Here the authors show that actin-microtubule interactions are essential for correct segregation of human nuclear genomic content.
ISSN:2041-1723