Bayesian detection of causal rare variants under posterior consistency.

Identification of causal rare variants that are associated with complex traits poses a central challenge on genome-wide association studies. However, most current research focuses only on testing the global association whether the rare variants in a given genomic region are collectively associated w...

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Bibliographic Details
Main Authors: Faming Liang, Momiao Xiong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724943?pdf=render