Altered Toll-Like Receptor-4 Response to Lipopolysaccharides in Infants Exposed to HIV-1 and Its Preventive Therapy

Altered Toll-Like Receptor-4 Response to Lipopolysaccharides in Infants Exposed to HIV-1 and Its Preventive Therapy

Pathogen sensing and recognition through pattern recognition receptors, and subsequent production of pro-inflammatory cytokines, is the cornerstone of the innate immune system. Despite the fact that HIV-exposed uninfected (HEU) infants are prone to serious bacterial infections, no study has focused...

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Bibliographic Details
Main Authors: Anicet Christel Maloupazoa Siawaya, Ofilia Mvoundza Ndjindji, Eliane Kuissi Kamgaing, Amandine Mveang-Nzoghe, Chérone Nancy Mbani Mpega, Marielle Leboueny, Roselyne Kengue Boussougou, Armel Mintsa Ndong, Paulin N. Essone, Joel Fleury Djoba Siawaya
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
infants
HIV-1
toll-like receptor-4
complement component-3
C-reactive protein
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00222/full

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