Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy

Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy

Bibliographic Details
Main Authors: Jimin Zhang, Meigui Deng, Xiaoguang Shi, Chuangnian Zhang, Xiongwei Qu, Xiuli Hu, Weiwei Wang, Deling Kong, Pingsheng Huang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-10-01
Series:Bioactive Materials
Subjects:
NO prodrug
Supramolecular hydrogel
Oxidative stress
Multidrug resistance
Synergistic therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21001067
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spelling doaj-0d6c27e20ba54c858dc797eb24f741112021-07-11T04:28:38ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2021-10-0161033003313Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapyJimin Zhang0Meigui Deng1Xiaoguang Shi2Chuangnian Zhang3Xiongwei Qu4Xiuli Hu5Weiwei Wang6Deling Kong7Pingsheng Huang8Hebei Key Laboratory of Functional Polymers, National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin, 300130, ChinaHebei Key Laboratory of Functional Polymers, National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin, 300130, ChinaTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, ChinaTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, ChinaHebei Key Laboratory of Functional Polymers, National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin, 300130, ChinaHebei Key Laboratory of Functional Polymers, National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin, 300130, China; Corresponding author.Tianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China; Corresponding author.State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences, Nankai University, Tianjin, 300071, ChinaTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, China; Corresponding author.http://www.sciencedirect.com/science/article/pii/S2452199X21001067NO prodrugSupramolecular hydrogelOxidative stressMultidrug resistanceSynergistic therapy
collection DOAJ
language English
format Article
sources DOAJ
author Jimin Zhang
Meigui Deng
Xiaoguang Shi
Chuangnian Zhang
Xiongwei Qu
Xiuli Hu
Weiwei Wang
Deling Kong
Pingsheng Huang
spellingShingle Jimin Zhang
Meigui Deng
Xiaoguang Shi
Chuangnian Zhang
Xiongwei Qu
Xiuli Hu
Weiwei Wang
Deling Kong
Pingsheng Huang
Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy
Bioactive Materials
NO prodrug
Supramolecular hydrogel
Oxidative stress
Multidrug resistance
Synergistic therapy
author_facet Jimin Zhang
Meigui Deng
Xiaoguang Shi
Chuangnian Zhang
Xiongwei Qu
Xiuli Hu
Weiwei Wang
Deling Kong
Pingsheng Huang
author_sort Jimin Zhang
title Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy
title_short Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy
title_full Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy
title_fullStr Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy
title_full_unstemmed Cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy
title_sort cascaded amplification of intracellular oxidative stress and reversion of multidrug resistance by nitric oxide prodrug based-supramolecular hydrogel for synergistic cancer chemotherapy
publisher KeAi Communications Co., Ltd.
series Bioactive Materials
issn 2452-199X
publishDate 2021-10-01
topic NO prodrug
Supramolecular hydrogel
Oxidative stress
Multidrug resistance
Synergistic therapy
url http://www.sciencedirect.com/science/article/pii/S2452199X21001067
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AT xiaoguangshi cascadedamplificationofintracellularoxidativestressandreversionofmultidrugresistancebynitricoxideprodrugbasedsupramolecularhydrogelforsynergisticcancerchemotherapy
AT chuangnianzhang cascadedamplificationofintracellularoxidativestressandreversionofmultidrugresistancebynitricoxideprodrugbasedsupramolecularhydrogelforsynergisticcancerchemotherapy
AT xiongweiqu cascadedamplificationofintracellularoxidativestressandreversionofmultidrugresistancebynitricoxideprodrugbasedsupramolecularhydrogelforsynergisticcancerchemotherapy
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AT delingkong cascadedamplificationofintracellularoxidativestressandreversionofmultidrugresistancebynitricoxideprodrugbasedsupramolecularhydrogelforsynergisticcancerchemotherapy
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