Quantitative Proteomic Profile of Psoriatic Epidermis Identifies OAS2 as a Novel Biomarker for Disease Activity

Quantitative Proteomic Profile of Psoriatic Epidermis Identifies OAS2 as a Novel Biomarker for Disease Activity

Psoriasis is a common chronic inflammatory systemic disease. Epidermal proteins are considered to be important in maintaining skin barrier function, innate immunity, and inflammation. To define more possible roles of the epidermis in the pathogenesis of psoriasis, quantified proteomic analysis was u...

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Bibliographic Details
Main Authors: Yuan Zhou, Ping Wang, Bing-Xi Yan, Xue-Yan Chen, Lilla Landeck, Zhao-Yuan Wang, Xin-Xin Li, Jing Zhang, Min Zheng, Xiao-Yong Man
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
psoriasis
proteomics
epidermis
iTRAQ
OAS2
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01432/full

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