Development of the insulin secretion mechanism in fetal and neonatal rat pancreatic B-cells: response to glucose, K+, theophylline, and carbamylcholine

We studied the development of the insulin secretion mechanism in the pancreas of fetal (19- and 21-day-old), neonatal (3-day-old), and adult (90-day-old) rats in response to stimulation with 8.3 or 16.7 mM glucose, 30 mM K+, 5 mM theophylline (Theo) and 200 µM carbamylcholine (Cch). No effect of glu...

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Bibliographic Details
Main Authors: A.C. Mendonça, E.M. Carneiro, J.R. Bosqueiro, S.C. Crepaldi-Alves, A.C. Boschero
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1998-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000600018