Oleanolic acid and ursolic acid inhibit peptidoglycan biosynthesis in Streptococcus mutans UA159

In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.

Bibliographic Details
Main Authors: Soon-Nang Park, Sug-Joon Ahn, Joong-Ki Kook
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia 2015-06-01
Series:Brazilian Journal of Microbiology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000200613&lng=en&tlng=en