The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids

Specific metabolic pathways are activated by different nutrients to adapt the organism to available resources. Although essential, these mechanisms are incompletely defined. Here, we report that medium-chain fatty acids contained in coconut oil, a major source of dietary fat, induce the liver ω-oxi...

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Bibliographic Details
Main Authors: Jun Ding, Ursula Loizides-Mangold, Gianpaolo Rando, Vincent Zoete, Olivier Michielin, Janardan K. Reddy, Walter Wahli, Howard Riezman, Bernard Thorens
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713004737