Voltammetric oxidation of dipyridamole in aqueous acid solutions

• Main Authors: Castilho Marilza, Almeida Luiz E., Tabak Marcel, Mazo Luiz H.
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Química 2000-01-01
• Series: Journal of the Brazilian Chemical Society
• Subjects: dipyridamole; anodic oxidation; cyclic voltammetry; aqueous acid solution
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532000000200008

The electrochemical oxidation of dipyridamole (DIP) has been studied in acidified aqueous solutions at platinum electrodes employing cyclic voltammetry and controlled-potential electrolysis. The progress of the anodic oxidation as a function of time was monitored by cyclic voltammetry with platinum ultramicroelectrodes, absorption and fluorescence optical spectroscopies, the resulting integrated charge being indicative of a two electron process. The cyclic voltammograms registered for low scan speeds are characterized by a single irreversible diffusion controlled anodic wave, the related cathodic wave being also observable for scan speeds higher than 1 V s-1. Oxidation reaction stoichiommetric parameters were obtained through Tafel slopes resulting in unitary reaction orders for DIP and H+.