Rapid Upregulation of Orai1 Abundance in the Plasma Membrane of Platelets Following Activation with Thrombin and Collagen Related Peptide

Rapid Upregulation of Orai1 Abundance in the Plasma Membrane of Platelets Following Activation with Thrombin and Collagen Related Peptide

Background: Blood platelets accomplish primary hemostasis following vascular injury and contribute to the orchestration of occlusive vascular disease. Platelets are activated by an increase of cytosolic Ca2+-activity ([Ca2+]i), which is accomplished by Ca2+-release from intracellular stores and subs...

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Bibliographic Details
Main Authors: Guilai Liu, Guoxing Liu, Hong Chen, Kousi Alzoubi, Anja T. Umbach, Meinrad Gawaz, Christos Stournaras, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
CRP
Cytosolic Ca2+ concentration
Rac1
SOCE
Online Access:http://www.karger.com/Article/FullText/438539

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