Extracellular Vesicles in Heart Disease: Excitement for the Future?

Extracellular Vesicles in Heart Disease: Excitement for the Future?

Extracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released from numerous cell types and are involved in intercellular communication, physiological functions and the pathology of disease. They have been shown to carry and transfer a wide range of cargo including...

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Main Authors: Kirsty M. Danielson, Saumya Das
Format: Article
Language:English
Published: AboutScience Srl 2014-01-01
Series:Journal of Circulating Biomarkers
Online Access:https://doi.org/10.5772/58390
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spelling doaj-0d24120ad97d4ba98cfe543319f2c1312020-11-25T03:06:27ZengAboutScience SrlJournal of Circulating Biomarkers1849-45442014-01-01210.5772/58390Extracellular Vesicles in Heart Disease: Excitement for the Future?Kirsty M. Danielson0Saumya Das1 Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, MA Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, MAExtracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released from numerous cell types and are involved in intercellular communication, physiological functions and the pathology of disease. They have been shown to carry and transfer a wide range of cargo including proteins, lipids and nucleic acids. The role of EVs in cardiac physiology and heart disease is an emerging field that has produced intriguing findings in recent years. This review will outline what is currently known about EVs in the cardiovascular system, including cellular origins, functional roles and utility as biomarkers and potential therapeutics.https://doi.org/10.5772/58390
collection DOAJ
language English
format Article
sources DOAJ
author Kirsty M. Danielson
Saumya Das
spellingShingle Kirsty M. Danielson
Saumya Das
Extracellular Vesicles in Heart Disease: Excitement for the Future?
Journal of Circulating Biomarkers
author_facet Kirsty M. Danielson
Saumya Das
author_sort Kirsty M. Danielson
title Extracellular Vesicles in Heart Disease: Excitement for the Future?
title_short Extracellular Vesicles in Heart Disease: Excitement for the Future?
title_full Extracellular Vesicles in Heart Disease: Excitement for the Future?
title_fullStr Extracellular Vesicles in Heart Disease: Excitement for the Future?
title_full_unstemmed Extracellular Vesicles in Heart Disease: Excitement for the Future?
title_sort extracellular vesicles in heart disease: excitement for the future?
publisher AboutScience Srl
series Journal of Circulating Biomarkers
issn 1849-4544
publishDate 2014-01-01
description Extracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released from numerous cell types and are involved in intercellular communication, physiological functions and the pathology of disease. They have been shown to carry and transfer a wide range of cargo including proteins, lipids and nucleic acids. The role of EVs in cardiac physiology and heart disease is an emerging field that has produced intriguing findings in recent years. This review will outline what is currently known about EVs in the cardiovascular system, including cellular origins, functional roles and utility as biomarkers and potential therapeutics.
url https://doi.org/10.5772/58390
work_keys_str_mv AT kirstymdanielson extracellularvesiclesinheartdiseaseexcitementforthefuture
AT saumyadas extracellularvesiclesinheartdiseaseexcitementforthefuture
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