Spinal cord injury causes chronic bone marrow failure

Spinal cord injury causes chronic bone marrow failure

Spinal cord injury (SCI) often leads to immune dysfunction, but mechanistic insights are still lacking. Here the authors show that SCI alters chemokine signaling and induces long, persisting defects in hematopoietic stem and progenitor cell migration, thereby entrapping them in the bone marrow and d...

Full description

Bibliographic Details
Main Authors: Randall S. Carpenter, Jessica M. Marbourg, Faith H. Brennan, Katherine A. Mifflin, Jodie C. E. Hall, Roselyn R. Jiang, Xiaokui M. Mo, Malith Karunasiri, Matthew H. Burke, Adrienne M. Dorrance, Phillip G. Popovich
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17564-z

Similar Items

Similar Items