dMyc functions downstream of Yorkie to promote the supercompetitive behavior of hippo pathway mutant cells.

Genetic analyses in Drosophila epithelia have suggested that the phenomenon of "cell competition" could participate in organ homeostasis. It has been speculated that competition between different cell populations within a growing organ might play a role as either tumor promoter or tumor su...

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Main Authors: Marcello Ziosi, Luis Alberto Baena-López, Daniela Grifoni, Francesca Froldi, Andrea Pession, Flavio Garoia, Vincenzo Trotta, Paola Bellosta, Sandro Cavicchi, Annalisa Pession
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2944792?pdf=render