Mitochondrial structure, function and dynamics are temporally controlled by c-Myc.

Mitochondrial structure, function and dynamics are temporally controlled by c-Myc.

Although the c-Myc (Myc) oncoprotein controls mitochondrial biogenesis and multiple enzymes involved in oxidative phosphorylation (OXPHOS), the coordination of these events and the mechanistic underpinnings of their regulation remain largely unexplored. We show here that re-expression of Myc in myc-...

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Bibliographic Details
Main Authors: J Anthony Graves, Yudong Wang, Sunder Sims-Lucas, Edward Cherok, Kristi Rothermund, Maria F Branca, Jennifer Elster, Donna Beer-Stolz, Bennett Van Houten, Jerry Vockley, Edward V Prochownik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3357432?pdf=render

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http://europepmc.org/articles/PMC3357432?pdf=render

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