<i>Tbx21</i> and <i>Foxp3</i> Are Epigenetically Stabilized in T-Bet<sup>+</sup> Tregs That Transiently Accumulate in Influenza A Virus-Infected Lungs

<i>Tbx21</i> and <i>Foxp3</i> Are Epigenetically Stabilized in T-Bet<sup>+</sup> Tregs That Transiently Accumulate in Influenza A Virus-Infected Lungs

During influenza A virus (IAV) infections, CD4<sup>+</sup> T cell responses within infected lungs mainly involve T helper 1 (Th1) and regulatory T cells (Tregs). Th1-mediated responses favor the co-expression of T-box transcription factor 21 (T-bet) in Foxp3<sup>+</sup> Tregs...

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Bibliographic Details
Main Authors: Yassin Elfaki, Juhao Yang, Julia Boehme, Kristin Schultz, Dunja Bruder, Christine S. Falk, Jochen Huehn, Stefan Floess
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
influenza A virus
Tregs
lung
inflammation
methylation
<i>Tbx21</i>
Online Access:https://www.mdpi.com/1422-0067/22/14/7522

Internet

https://www.mdpi.com/1422-0067/22/14/7522

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