Unraveling the Photodynamic Activity of Cationic Benzoporphyrin-Based Photosensitizers against Bladder Cancer Cells

Unraveling the Photodynamic Activity of Cationic Benzoporphyrin-Based Photosensitizers against Bladder Cancer Cells

In this study, we report the preparation of new mono-charged benzoporphyrin complexes by reaction of the appropriate neutral benzoporphyrin with (2,2′-bipyridine)dichloroplatinum(II) and of the analogs’ derivatives synthesized through alkylation of the neutral scaffold with iodomethane. All derivati...

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Bibliographic Details
Main Authors: Ana T. P. C. Gomes, M. Graça P. M. S. Neves, Rosa Fernandes, Carlos F. Ribeiro, José A. S. Cavaleiro, Nuno M. M. Moura
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
benzoporphyrin
photosensitizer
platinum complexes
cancer
photodynamic therapy
Online Access:https://www.mdpi.com/1420-3049/26/17/5312

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