Principal cell activity induces spine relocation of adult-born interneurons in the olfactory bulb

Principal cell activity induces spine relocation of adult-born interneurons in the olfactory bulb

The mechanism by which adult-born neurons quickly adjust olfactory bulb network functioning is not understood. Here the authors describe a novel form of structural plasticity in which mature spines relocate toward active mitral cell dendrite along spine head filopodia via AMPA and BDNF mediated sign...

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Bibliographic Details
Main Authors: Vincent Breton-Provencher, Karen Bakhshetyan, Delphine Hardy, Rodrigo Roberto Bammann, Francesco Cavarretta, Marina Snapyan, Daniel Côté, Michele Migliore, Armen Saghatelyan
Format: Article
Language:English
Published: Nature Publishing Group 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12659
Description
Summary:The mechanism by which adult-born neurons quickly adjust olfactory bulb network functioning is not understood. Here the authors describe a novel form of structural plasticity in which mature spines relocate toward active mitral cell dendrite along spine head filopodia via AMPA and BDNF mediated signalling.
ISSN:2041-1723

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