Defining the genomic signature of totipotency and pluripotency during early human development.

Defining the genomic signature of totipotency and pluripotency during early human development.

The genetic mechanisms governing human pre-implantation embryo development and the in vitro counterparts, human embryonic stem cells (hESCs), still remain incomplete. Previous global genome studies demonstrated that totipotent blastomeres from day-3 human embryos and pluripotent inner cell masses (I...

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Bibliographic Details
Main Authors: Amparo Galan, Patricia Diaz-Gimeno, Maria Eugenia Poo, Diana Valbuena, Eva Sanchez, Veronica Ruiz, Joaquin Dopazo, David Montaner, Ana Conesa, Carlos Simon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23614026/?tool=EBI

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