Physical Biomarkers of Disease Progression: On-Chip Monitoring of Changes in Mechanobiology of Colorectal Cancer Cells
Abstract Disease can induce changes to subcellular components, altering cell phenotype and leading to measurable bulk-material mechanical properties. The mechanical phenotyping of single cells therefore offers many potential diagnostic applications. Cells are viscoelastic and their response to an ap...
Main Authors: | Fern J. Armistead, Julia Gala De Pablo, Hermes Gadêlha, Sally A. Peyman, Stephen D. Evans |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-59952-x |
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