Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed

Today's biomedicine builds on the conviction that biochemistry can explain the creation of the body, its anatomy and physiology. Unfortunately there are still deep mysteries strangely “fighting back” when we try to define and understand the organism and its creation in the ontogenesis as emergi...

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Main Authors: Søren Ventegodt, Tyge Dahl Hermansen, Trine Flensborg-Madsen, Maj Lyck Nielsen, Birgitte Clausen, Joav Merrick
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2006.234
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spelling doaj-0cfd7295807942ae8ddb41ebb647e10b2020-11-25T00:48:42ZengHindawi LimitedThe Scientific World Journal1537-744X2006-01-0161359136710.1100/tsw.2006.234Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is NeededSøren Ventegodt0Tyge Dahl Hermansen1Trine Flensborg-Madsen2Maj Lyck Nielsen3Birgitte Clausen4Joav Merrick5Quality of Life Research Center, Teglgårdstræde 4-8, DK-1452 Copenhagen K, DenmarkQuality of Life Research Center, Teglgårdstræde 4-8, DK-1452 Copenhagen K, DenmarkQuality of Life Research Center, Teglgårdstræde 4-8, DK-1452 Copenhagen K, DenmarkQuality of Life Research Center, Teglgårdstræde 4-8, DK-1452 Copenhagen K, DenmarkVejlby Lokalcenter, Vejlby, DenmarkInteruniversity College, Graz, AustriaToday's biomedicine builds on the conviction that biochemistry can explain the creation of the body, its anatomy and physiology. Unfortunately there are still deep mysteries strangely “fighting back” when we try to define and understand the organism and its creation in the ontogenesis as emerging from biochemistry. In analysing this from a theoretical perspective using a mathematical model focusing on the noise in complex chemical systems we argue that evolving biological structure cannot in principle be a product of chemistry. In this paper we go through the chemical gradient model and argue that this is not able to explain the ontogenesis. We discuss the used gradients as information carriers in chemical self-organizing systems and argue that by use of the “Turing structures” we are only able to modelling the mostly simple biological systems. The bio-chemical model is only able to model simple organization but not to explain the complexity of biological phenomena. We conclude that we seemingly have presented a formal proof (a NO-GO theorem) that the self-organizing chemical systems that are using chemical gradients are not able to explain complex biological matters as the ontogenesis. We need a fundamentally new, information-carrying principle to understand biological information and biological order.http://dx.doi.org/10.1100/tsw.2006.234
collection DOAJ
language English
format Article
sources DOAJ
author Søren Ventegodt
Tyge Dahl Hermansen
Trine Flensborg-Madsen
Maj Lyck Nielsen
Birgitte Clausen
Joav Merrick
spellingShingle Søren Ventegodt
Tyge Dahl Hermansen
Trine Flensborg-Madsen
Maj Lyck Nielsen
Birgitte Clausen
Joav Merrick
Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed
The Scientific World Journal
author_facet Søren Ventegodt
Tyge Dahl Hermansen
Trine Flensborg-Madsen
Maj Lyck Nielsen
Birgitte Clausen
Joav Merrick
author_sort Søren Ventegodt
title Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed
title_short Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed
title_full Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed
title_fullStr Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed
title_full_unstemmed Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed
title_sort human development v: biochemistry unable to explain the emergence of biological form (morphogenesis) and therefore a new principle as source of biological information is needed
publisher Hindawi Limited
series The Scientific World Journal
issn 1537-744X
publishDate 2006-01-01
description Today's biomedicine builds on the conviction that biochemistry can explain the creation of the body, its anatomy and physiology. Unfortunately there are still deep mysteries strangely “fighting back” when we try to define and understand the organism and its creation in the ontogenesis as emerging from biochemistry. In analysing this from a theoretical perspective using a mathematical model focusing on the noise in complex chemical systems we argue that evolving biological structure cannot in principle be a product of chemistry. In this paper we go through the chemical gradient model and argue that this is not able to explain the ontogenesis. We discuss the used gradients as information carriers in chemical self-organizing systems and argue that by use of the “Turing structures” we are only able to modelling the mostly simple biological systems. The bio-chemical model is only able to model simple organization but not to explain the complexity of biological phenomena. We conclude that we seemingly have presented a formal proof (a NO-GO theorem) that the self-organizing chemical systems that are using chemical gradients are not able to explain complex biological matters as the ontogenesis. We need a fundamentally new, information-carrying principle to understand biological information and biological order.
url http://dx.doi.org/10.1100/tsw.2006.234
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