Penduliflaworosin, a Diterpenoid from Croton crassifolius, Exerts Anti-Angiogenic Effect via VEGF Receptor-2 Signaling Pathway
Anti-angiogenesis targeting vascular endothelial growth factor receptor-2 (VEGFR-2) has been considered as an important strategy for cancer therapy. Penduliflaworosin is a diterpenoid isolated from the plant Croton crassifolius. Our previous study showed that this diterpenoid possesses strong anti-a...
Main Authors: | Yeyin Liang, Yubo Zhang, Guocai Wang, Yaolan Li, Weihuan Huang |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-01-01
|
Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/22/1/126 |
Similar Items
-
Crassifolins Q−W: Clerodane Diterpenoids From Croton crassifolius With Anti-Inflammatory and Anti-Angiogenesis Activities
by: Canjie Li, et al.
Published: (2021-09-01) -
Anti-Angiogenic Effect of Asperchalasine A Via Attenuation of VEGF Signaling
by: Jun Yeon Park, et al.
Published: (2019-08-01) -
Old Player-New Tricks: Non Angiogenic Effects of the VEGF/VEGFR Pathway in Cancer
by: Panagiotis Ntellas, et al.
Published: (2020-10-01) -
VEGF Regulation of Angiogenic Factors via Inflammatory Signaling in Myeloproliferative Neoplasms
by: Tijana Subotički, et al.
Published: (2021-06-01) -
Biological Pathways Involved in Tumor Angiogenesis and Bevacizumab Based Anti-Angiogenic Therapy with Special References to Ovarian Cancer
by: Vera Loizzi, et al.
Published: (2017-09-01)