The critical role of partially exposed N-terminal valine residue in stabilizing GH10 xylanase from Bacillus sp.NG-27 under poly-extreme conditions.

The critical role of partially exposed N-terminal valine residue in stabilizing GH10 xylanase from Bacillus sp.NG-27 under poly-extreme conditions.

BACKGROUND: Understanding the mechanisms that govern protein stability under poly-extreme conditions continues to be a major challenge. Xylanase (BSX) from Bacillus sp. NG-27, which has a TIM-barrel structure, shows optimum activity at high temperature and alkaline pH, and is resistant to denaturati...

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Bibliographic Details
Main Authors: Amit Bhardwaj, Sadhu Leelavathi, Sudeshna Mazumdar-Leighton, Amit Ghosh, Suryanarayanarao Ramakumar, Vanga S Reddy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2516601?pdf=render

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http://europepmc.org/articles/PMC2516601?pdf=render

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