Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat[S]

Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat[S]

Vaccenic acid (VA), the predominant ruminant-derived trans fat in the food chain, ameliorates hyperlipidemia, yet mechanisms remain elusive. We investigated whether VA could influence tissue endocannabinoids (ECs) by altering the availability of their biosynthetic precursor, arachidonic acid (AA), i...

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Bibliographic Details
Main Authors: Miriam Jacome-Sosa, Claudia Vacca, Rabban Mangat, Abdoulaye Diane, Randy C. Nelson, Martin J. Reaney, Jianheng Shen, Jonathan M. Curtis, Donna F. Vine, Catherine J. Field, Miki Igarashi, Daniele Piomelli, Sebastiano Banni, Spencer D. Proctor
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Lipid Research
Subjects:
vaccenic acid
endocannabinoids
N-acylethanolamines
intestinal inflammatory diseases
anandamide
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520354195

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