Combining specificity determining and conserved residues improves functional site prediction
<p>Abstract</p> <p>Background</p> <p>Predicting the location of functionally important sites from protein sequence and/or structure is a long-standing problem in computational biology. Most current approaches make use of sequence conservation, assuming that amino acid r...
Main Authors: | Gelfand Mikhail S, Kalinina Olga V, Russell Robert B |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-06-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/10/174 |
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