Combining specificity determining and conserved residues improves functional site prediction

<p>Abstract</p> <p>Background</p> <p>Predicting the location of functionally important sites from protein sequence and/or structure is a long-standing problem in computational biology. Most current approaches make use of sequence conservation, assuming that amino acid r...

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Bibliographic Details
Main Authors: Gelfand Mikhail S, Kalinina Olga V, Russell Robert B
Format: Article
Language:English
Published: BMC 2009-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/10/174

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