Japanese medaka: a non-mammalian vertebrate model for studying sex and age-related bone metabolism in vivo.

Japanese medaka: a non-mammalian vertebrate model for studying sex and age-related bone metabolism in vivo.

BACKGROUND: In human, a reduction in estrogen has been proposed as one of the key contributing factors for postmenopausal osteoporosis. Rodents are conventional models for studying postmenopausal osteoporosis, but the major limitation is that ovariectomy is needed to mimic the estrogen decline after...

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Bibliographic Details
Main Authors: Admane H Shanthanagouda, Bao-Sheng Guo, Rui R Ye, Liang Chao, Michael W L Chiang, Gopalakrishnan Singaram, Napo K M Cheung, Ge Zhang, Doris W T Au
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3921145?pdf=render

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