Middle-term bowel function and quality of life in low-type anorectal malformation

• Main Authors: Haiqing Zheng, Guangjian Liu, Zijian Liang, Yunpei Chen, Zhe Wen, Jiakang Yu, Xiaogang Xu, Huiying Liang, Yong Wang
• Format: Article
• Language: English
• Published: BMC 2019-08-01
• Series: Italian Journal of Pediatrics
• Subjects: Low-type anorectal malformations; Bowel function; Quality of life; Vestibular fistula; Perineal fistula
• Online Access: http://link.springer.com/article/10.1186/s13052-019-0701-3

Abstract Background Low-type anorectal malformations (ARMs) are considered benign; however, in China, data regarding such conditions are limited. Thus, this study aimed to assess the middle-term bowel functions and quality of life (QOL) among children with low-type ARM. Methods Children > 3 years of age who underwent treatment for low-type ARM (vestibular fistula [VF] and perineal fistula [PF]) during 2013 and healthy children were included. The children were interviewed during their outpatient visits. The primary outcome measures were bowel function, as assessed using the Baylor Continence Scale (BCS), and QOL, as measured using the Pediatric Quality of Life Inventory (PedsQL 4.0). Results A total of 82 patients responded; mean patient age was 6.8 (range, 3–12) years. Mean BCS score in the control group (7.94 ± 4.74) was significantly lower than that in the VF (18.69 ± 11.11, P < 0.001) and PF (15.47 ± 6.50, P < 0.001) groups. However, there were no differences in PedsQL 4.0 scores among the groups. The patients scored the lowest for emotional function and the highest for physical function. Nearly all measurements of QOL significantly decreased with increased BCS score. Conclusions Children with low-type ARM can achieve good bowel control and QOL. However, although ARMs are benign, several children with this condition suffer from anal function problems that affect QOL. Redo operations, mislocated anus, and incorrect constipation treatment are the iatrogenic causes of fecal incontinence.