Efficient Delivery of Therapeutic siRNA with Nanoparticles Induces Apoptosis in Prostate Cancer Cells

Efficient Delivery of Therapeutic siRNA with Nanoparticles Induces Apoptosis in Prostate Cancer Cells

Gene silencing using small interfering RNA (siRNA) has shown significant potential in the treatment of cancer. Herein, we developed the lipid-polymer hybrid nanoparticles (PEG-LP/siRNA NPs) for siRNA delivery. The cell viability assay indicated that PEG-LP/siRNA NPs had negligible cell cytotoxicity....

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Bibliographic Details
Main Authors:	Xupeng Mu, Haibin Lu, Lianlian Fan, Shaohua Yan, Kebang Hu
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Journal of Nanomaterials
Online Access:	http://dx.doi.org/10.1155/2018/4719790

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