Characterization of a Suppressive Cis-acting Element in the Epstein–Barr Virus LMP1 Promoter

Characterization of a Suppressive Cis-acting Element in the Epstein–Barr Virus LMP1 Promoter

Latent membrane protein 1 (LMP1) is a major oncogene encoded by Epstein–Barr virus (EBV) and is essential for immortalization of B cells by the virus. Previous studies suggested that several transcription factors, such as PU.1, RBP-Jκ, NFκB, EBF1, AP-2 and STAT, are involved in LMP1 induction; howev...

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Bibliographic Details
Main Authors: Masahiro Yoshida, Takayuki Murata, Keiji Ashio, Yohei Narita, Takahiro Watanabe, H. M. Abdullah Al Masud, Yoshitaka Sato, Fumi Goshima, Hiroshi Kimura
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Microbiology
Subjects:
EBV
LMP1
promoter
transcription
EBV-BAC
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02302/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.02302/full

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