Lipids bearing extruded-spheronized pellets for extended release of poorly soluble antiemetic agent—Meclizine HCl

Lipids bearing extruded-spheronized pellets for extended release of poorly soluble antiemetic agent—Meclizine HCl

Abstract Background Antiemetic agent Meclizine HCl, widely prescribed in vertigo, is available only in immediate release dosage forms. The approved therapeutic dose and shorter elimination half-life make Meclizine HCl a potential candidate to be formulated in extended release dosage form. This study...

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Bibliographic Details
Main Authors: Faaiza Qazi, Muhammad Harris Shoaib, Rabia Ismail Yousuf, Muhammad Iqbal Nasiri, Kamran Ahmed, Mansoor Ahmad
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Lipids in Health and Disease
Subjects:
Meclizine HCl
Pellets
Lipids
Extended release
Extrusion spheronization
Online Access:http://link.springer.com/article/10.1186/s12944-017-0466-x

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