Energy profile and secondary structure impact shRNA efficacy
<p>Abstract</p> <p>Background</p> <p>RNA interference (RNAi) is a cellular mechanism in which a short/small double stranded RNA induces the degradation of its sequence specific target mRNA, leading to specific gene silencing. Since its discovery, RNAi has become a power...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-07-01
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| Series: | BMC Genomics |