Assessment of protective effect of ascorbic acid in cisplatin ototoxicity on guinea pigs with electrophysiological tests and ultrastructural study: A Preliminary Study

Assessment of protective effect of ascorbic acid in cisplatin ototoxicity on guinea pigs with electrophysiological tests and ultrastructural study: A Preliminary Study

Objective: It was aimed to display ascorbic acid’s protective efficiency in preventing ototoxicity caused by cisplatin use with electrophysiological tests (Transient Evoked Otoacoustic Emission and Auditory Brainstem Responses) and ultrastructural study (light and electron microscopic). Methods: As...

Full description

Bibliographic Details
Main Author:	Safiye G. Ortekin, Murat Kocyigit, Recep Yagiz, Abdullah Tas, Erdogan Bulut, Muhsin Koten, Mehmet Kanter, Ahmet Rıfat Karasalihoglu
Format:	Article
Language:	English
Published:	Bulgarian Association of Young Surgeons 2019-04-01
Series:	International Journal of Surgery and Medicine
Subjects:	cisplatin ascorbic acid ototoxicity
Online Access:	http://www.ejos.org/index.php?fulltxt=26760&fulltxtj=136&fulltxtp=136-1547736802.pdf

Similar Items

Cisplatin ototoxicity histopathology
by: Sarah E. Hodge, et al.
Published: (2021-08-01)

The Effect of Dexpanthenol on Ototoxicity Induced by Cisplatin
by: Yuksel Toplu, et al.
Published: (2016-03-01)

Cisplatin-induced ototoxicity: the current state of ototoxicity monitoring in New Zealand.
by: Venter, Kinau
Published: (2011)

Mechanisms of Cisplatin-Induced Ototoxicity and Otoprotection
by: Sandeep Sheth, et al.
Published: (2017-10-01)

The protective effect of coumaric acid against cisplatin-induced ototoxicity in rats
by: Fazile Nur Ekinci Akdemir, et al.
Published: (2018-06-01)

Is Hyperbaric Oxygen Therapy Effective in Cisplatin-Induced Ototoxicity in Rats?
by: H. Bengu Cobanoglu, et al.
Published: (2019-02-01)

Protective Effect of Tempol against Cisplatin-Induced Ototoxicity
by: Cha Kyung Youn, et al.
Published: (2016-11-01)

Protective effect of capsaicin against cisplatin ototoxicity
by: Bhatta, Puspanjali
Published: (2014)

TARGETING COCHLEAR INFLAMMATION FOR THE TREATMENT OF CISPLATIN OTOTOXICITY
by: Kaur, Tejbeer
Published: (2012)

The Effects of Riluzole on Cisplatin-induced Ototoxicity
by: Selin Üstün Bezgin, et al.
Published: (2019-03-01)

Cisplatin-Induced Ototoxicity: Effects, Mechanisms and Protection Strategies
by: Angela Callejo, et al.
Published: (2015-07-01)

The efficacy of strategies used to minimise or prevent Cisplatin-induced ototoxicity in patients
by: Zenzo S. Chakara, et al.
Published: (2019-01-01)

Opa1 Prevents Apoptosis and Cisplatin-Induced Ototoxicity in Murine Cochleae
by: Tingting Dong, et al.
Published: (2021-09-01)

Insight into the current practice of ototoxicity monitoring during cisplatin therapy
by: N. M. Santucci, et al.
Published: (2021-03-01)

Cisplatin Ototoxicity: Examination of the Impact of Dosing, Infusion Times, and Schedules In Pediatric Cancer Patients
by: Miranda L. Camet, et al.
Published: (2021-06-01)

Radiotherapy-enhanced ototoxicity in elderly
by: Monika S Malgonde, et al.
Published: (2014-01-01)

Current Strategies to Combat Cisplatin-Induced Ototoxicity
by: Dehong Yu, et al.
Published: (2020-07-01)

Ototoxicity: A review of South African studies
by: Selvarani Moodley, et al.
Published: (2021-03-01)

Cisplatin-Induced Ototoxicity in Rats Is Driven by RIP3-Dependent Necroptosis
by: Mi-Jin Choi, et al.
Published: (2019-05-01)

Editorial: Cellular Mechanisms of Ototoxicity
by: Peter S. Steyger, et al.
Published: (2018-03-01)

High incidence of cisplatin-induced ototoxicity in paediatric patients in the Western Cape, South Africa
by: Mukovhe Phanguphangu, et al.
Published: (2018-07-01)

A Dose-Effect Study of Cisplatin Ototoxicity in Albino Guinea Pigs
by: Negin Salehi, et al.
Published: (2020-05-01)

Ototoxicity of Non-aminoglycoside Antibiotics
by: Leonard P. Rybak, et al.
Published: (2021-03-01)

Feasibility and first results of a prospective cohort study to investigate cisplatin-associated ototoxicity amongst cancer patients in South Africa
by: Jessica Paken, et al.
Published: (2021-07-01)

Is Cyclosporine Ototoxic?
by: Sofia Waissbluth
Published: (2020-10-01)

Anti-apoptotic effect of dexamethasone in an ototoxicity model
by: Jin Ho Lee, et al.
Published: (2017-04-01)

Protective effect of lutein against acrolein-induced ototoxicity in rats
by: Ertugrul Erhan, et al.
Published: (2021-05-01)

Antimaláricos e Ototoxicidade Antimalarials and Ototoxicity
by: Marcelo Cardoso Figueiredo, et al.
Published: (2004-06-01)

Mechanism and Prevention of Ototoxicity Induced by Aminoglycosides
by: Xiaolong Fu, et al.
Published: (2021-06-01)

Baseline audiological profiling of South African females with cervical cancer: an important attribute for assessing cisplatin-associated ototoxicity
by: Jessica Paken, et al.
Published: (2021-04-01)

Aminoglycoside induced ototoxicity associated with mitochondrial DNA mutations
by: Joseph Foster II, et al.
Published: (2016-07-01)

Targeting nitrative stress for attenuating cisplatin-induced downregulation of cochlear LIM domain only 4 and ototoxicity
by: Samson Jamesdaniel, et al.
Published: (2016-12-01)

Protein Synthesis Inhibition and Activation of the c-Jun N-Terminal Kinase Are Potential Contributors to Cisplatin Ototoxicity
by: Brian D. Nicholas, et al.
Published: (2017-09-01)

Protective Effects of Glucose-Related Protein 78 and 94 on Cisplatin-Mediated Ototoxicity
by: Junyeong Yi, et al.
Published: (2020-08-01)

Ototoxicity in patients receiving concurrent cisplatin and cranial irradiation therapy for the treatment of head and neck cancers: an audiometric follow-up
by: Alchin, Katrine Felice
Published: (2010)

Ototoxicity Monitoring using Automated Extended High-Frequency Audiometry and the Sensitive Range of Ototoxicity in Patients with MDR-TB
by: Greeff, Wildine Marion
Published: (2021)

Research protocol: Cisplatin-associated ototoxicity amongst patients receiving cancer chemotherapy and the feasibility of an audiological monitoring program
by: J. Paken, et al.
Published: (2017-12-01)

Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects
by: German Nacher-Soler, et al.
Published: (2021-07-01)

Role of otoacoustic emissions in the early detection and prevention of ototoxicity
by: Anil Kaul, et al.
Published: (2018-01-01)

Low early ototoxicity rates for pediatric medulloblastoma patients treated with proton radiotherapy
by: Gidley Paul W, et al.
Published: (2011-06-01)