Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension

Background and aims: An important factor in the development of vascular wall lesions is the degradation of the major protein of connective tissue - type IV collagen. Type IV collagen peptides (CIVDP) derived from this degradation are present in the circulation and are a stimulus for production of an...

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Main Authors:	Nikolov Asparuh, Tzekova Maria, Blazhev Alexander
Format:	Article
Language:	English
Published:	Pensoft Publishers 2019-06-01
Series:	Folia Medica
Subjects:	diabetes mellitus arterial hypertension anti-elastin antibodies (IgG, IgM, IgA) micro-angiopathy lipid indices
Online Access:	http://www.degruyter.com/view/j/folmed.2018.61.issue-2/folmed-2018-0072/folmed-2018-0072.xml?format=INT

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spelling	doaj-0cb6fafcfe384fe1991b2ab142f541af2020-11-25T01:39:10ZengPensoft PublishersFolia Medica 1314-21432019-06-0161223123910.2478/folmed-2018-0072folmed-2018-0072Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial HypertensionNikolov Asparuh0Tzekova Maria1Blazhev Alexander2Institute for Scientific Research, Medical University, Pleven, BulgariaDepartment of Propedeutics of Internal Diseases, Medical University, Pleven, BulgariaDivision of Biology, Medical University, Pleven, BulgariaBackground and aims: An important factor in the development of vascular wall lesions is the degradation of the major protein of connective tissue - type IV collagen. Type IV collagen peptides (CIVDP) derived from this degradation are present in the circulation and are a stimulus for production of anti-collagen type IV antibodies (ACIVAbs) IgM, IgG and IgA. The aim of this study was to find a possible association between ACIVAbs, lipid indices and the development of microvascular complications.http://www.degruyter.com/view/j/folmed.2018.61.issue-2/folmed-2018-0072/folmed-2018-0072.xml?format=INTdiabetes mellitusarterial hypertensionanti-elastin antibodies (IgG, IgM, IgA)micro-angiopathylipid indices
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Nikolov Asparuh Tzekova Maria Blazhev Alexander
spellingShingle	Nikolov Asparuh Tzekova Maria Blazhev Alexander Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension Folia Medica diabetes mellitus arterial hypertension anti-elastin antibodies (IgG, IgM, IgA) micro-angiopathy lipid indices
author_facet	Nikolov Asparuh Tzekova Maria Blazhev Alexander
author_sort	Nikolov Asparuh
title	Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension
title_short	Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension
title_full	Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension
title_fullStr	Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension
title_full_unstemmed	Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension
title_sort	relationship between lipid indices, type iv collagen turnover and the development of microvascular complications in diabetic patients with arterial hypertension
publisher	Pensoft Publishers
series	Folia Medica
issn	1314-2143
publishDate	2019-06-01
description	Background and aims: An important factor in the development of vascular wall lesions is the degradation of the major protein of connective tissue - type IV collagen. Type IV collagen peptides (CIVDP) derived from this degradation are present in the circulation and are a stimulus for production of anti-collagen type IV antibodies (ACIVAbs) IgM, IgG and IgA. The aim of this study was to find a possible association between ACIVAbs, lipid indices and the development of microvascular complications.
topic	diabetes mellitus arterial hypertension anti-elastin antibodies (IgG, IgM, IgA) micro-angiopathy lipid indices
url	http://www.degruyter.com/view/j/folmed.2018.61.issue-2/folmed-2018-0072/folmed-2018-0072.xml?format=INT
work_keys_str_mv	AT nikolovasparuh relationshipbetweenlipidindicestypeivcollagenturnoverandthedevelopmentofmicrovascularcomplicationsindiabeticpatientswitharterialhypertension AT tzekovamaria relationshipbetweenlipidindicestypeivcollagenturnoverandthedevelopmentofmicrovascularcomplicationsindiabeticpatientswitharterialhypertension AT blazhevalexander relationshipbetweenlipidindicestypeivcollagenturnoverandthedevelopmentofmicrovascularcomplicationsindiabeticpatientswitharterialhypertension
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Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension

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