Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension

Relationship between Lipid Indices, Type IV Collagen Turnover and the Development of Microvascular Complications in Diabetic Patients with Arterial Hypertension

Background and aims: An important factor in the development of vascular wall lesions is the degradation of the major protein of connective tissue - type IV collagen. Type IV collagen peptides (CIVDP) derived from this degradation are present in the circulation and are a stimulus for production of an...

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Bibliographic Details
Main Authors: Nikolov Asparuh, Tzekova Maria, Blazhev Alexander
Format: Article
Language:English
Published: Pensoft Publishers 2019-06-01
Series:Folia Medica
Subjects:
diabetes mellitus
arterial hypertension
anti-elastin antibodies (IgG, IgM, IgA)
micro-angiopathy
lipid indices
Online Access:http://www.degruyter.com/view/j/folmed.2018.61.issue-2/folmed-2018-0072/folmed-2018-0072.xml?format=INT
Description
Summary:Background and aims: An important factor in the development of vascular wall lesions is the degradation of the major protein of connective tissue - type IV collagen. Type IV collagen peptides (CIVDP) derived from this degradation are present in the circulation and are a stimulus for production of anti-collagen type IV antibodies (ACIVAbs) IgM, IgG and IgA. The aim of this study was to find a possible association between ACIVAbs, lipid indices and the development of microvascular complications.
ISSN:1314-2143

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