Investigation on the Alteration of Brain Functional Network and Its Role in the Identification of Mild Cognitive Impairment

Investigation on the Alteration of Brain Functional Network and Its Role in the Identification of Mild Cognitive Impairment

Mild cognitive impairment (MCI) is generally regarded as a prodromal stage of Alzheimer’s disease (AD). In coping with the challenges caused by AD, we analyzed resting-state functional magnetic resonance imaging data of 82 MCI subjects and 93 normal controls (NCs). The alteration of brain functional...

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Bibliographic Details
Main Authors: Lulu Zhang, Huangjing Ni, Zhinan Yu, Jun Wang, Jiaolong Qin, Fengzhen Hou, Albert Yang, Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
mild cognitive impairment
resting-state functional MRI
modular structure
graph theory
machine learning
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.558434/full

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