Development of PET Radioligands Targeting COX-2 for Colorectal Cancer Staging, a Review of in vitro and Preclinical Imaging Studies

Development of PET Radioligands Targeting COX-2 for Colorectal Cancer Staging, a Review of in vitro and Preclinical Imaging Studies

Colorectal cancer (CRC) is the second most common cause of cancer death, making early diagnosis a major public health challenge. The role of inflammation in tumorigenesis has been extensively explored, and among the identified markers of inflammation, cyclooxygenase-2 (COX-2) expression seems to be...

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Bibliographic Details
Main Authors: Caroline Dagallier, François Avry, Yann Touchefeu, Frédéric Buron, Sylvain Routier, Michel Chérel, Nicolas Arlicot
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Medicine
Subjects:
COX-2
PET
colorectal cancer
radioligands
preclinical model
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.675209/full

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