New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy

New Drug Candidate Targeting the 4A1 Orphan Nuclear Receptor for Medullary Thyroid Cancer Therapy

Medullary thyroid cancer (MTC) is a relatively rare thyroid cancer responsible for a substantial fraction of thyroid cancer mortality. More effective therapeutic drugs with low toxicity for MTC are urgently needed. Orphan nuclear receptor 4A1 (NR4A1) plays a pivotal role in regulating the proliferat...

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Bibliographic Details
Main Authors:	Lei Zhang, Wen Liu, Qun Wang, Qinpei Li, Huijuan Wang, Jun Wang, Tieshan Teng, Mingliang Chen, Ailing Ji, Yanzhang Li
Format:	Article
Language:	English
Published:	MDPI AG 2018-03-01
Series:	Molecules
Subjects:	orphan nuclear receptor 4A1 (NR4A1) thyroid cancer 2-imino-6-methoxy-2H-chromene-3-carbothioamide (IMCA)
Online Access:	http://www.mdpi.com/1420-3049/23/3/565

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