A novel rabbit immunospot array assay on a chip allows for the rapid generation of rabbit monoclonal antibodies with high affinity.

A novel rabbit immunospot array assay on a chip allows for the rapid generation of rabbit monoclonal antibodies with high affinity.

Antigen-specific rabbit monoclonal antibodies (RaMoAbs) are useful due to their high specificity and high affinity, and the establishment of a comprehensive and rapid RaMoAb generation system has been highly anticipated. Here, we present a novel system using immunospot array assay on a chip (ISAAC)...

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Bibliographic Details
Main Authors: Tatsuhiko Ozawa, Xiuhong Piao, Eiji Kobayashi, Yue Zhou, Hiroaki Sakurai, Tsugunobu Andoh, Aishun Jin, Hiroyuki Kishi, Atsushi Muraguchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3530603?pdf=render

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