Production of Carbapenemases in Klebsiella pneumoniae Isolated in Saint-Petersburg
Carbapenem-resistant nosocomial K. pneumoniae isolates are a significant problem in clinical practice. Carbapenem resistance in K. pneumoniae isolated from hospitalized patients was 2.8% over the study period. NDM-1 carbapenemase-producing strains were the most prevalent ones. K. pneumoniae strains...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy
2016-08-01
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| Series: | Клиническая микробиология и антимикробная химиотерапия |
| Subjects: | |
| Online Access: | https://cmac-journal.ru/publication/2016/3/cmac-2016-t18-n3-p196/cmac-2016-t18-n3-p196.pdf |
| Summary: | Carbapenem-resistant nosocomial K. pneumoniae isolates are a significant problem in clinical practice. Carbapenem resistance in K. pneumoniae isolated from hospitalized patients was 2.8% over the study period. NDM-1 carbapenemase-producing strains were the most prevalent ones. K. pneumoniae strains with OXA-48 were isolated more rarely, and KPC-2 was determined in 2 cases. NDM-1 gene was detected in multiple K. pneumoniae sequence types (ST340, ST147, ST11, ST307). OXA-48 gene was determined in K. pneumoniae ST395 and KPC-2 gene was determined in K. pneumoniae ST15 and ST258. |
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| ISSN: | 1684-4386 2686-9586 |