A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid

A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid

The microstructure and dissolubility of a calcified enterolith and enterolith pieces removed from a 26-year-old Japanese woman with Crohn’s disease were analyzed using scanning electron microscopy and energy dispersive X-ray spectroscopy. The enterolith showed a multilayered structure with fatty aci...

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Main Authors: Masaya Iwamuro, Haruo Urata, Sakiko Hiraoka, Masayasu Ohmori, Yoshitaka Kondo, Yoshiro Kawahara, Hiroyuki Okada
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2017/2951547
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spelling doaj-0ca6feadc3d348ef9dcf609816d5c8ba2020-11-24T23:12:03ZengHindawi LimitedCase Reports in Gastrointestinal Medicine2090-65282090-65362017-01-01201710.1155/2017/29515472951547A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric AcidMasaya Iwamuro0Haruo Urata1Sakiko Hiraoka2Masayasu Ohmori3Yoshitaka Kondo4Yoshiro Kawahara5Hiroyuki Okada6Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, JapanCentral Research Laboratory, Okayama University Medical School, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, JapanDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, JapanDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, JapanDepartment of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, JapanDepartment of Endoscopy, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, JapanDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, JapanThe microstructure and dissolubility of a calcified enterolith and enterolith pieces removed from a 26-year-old Japanese woman with Crohn’s disease were analyzed using scanning electron microscopy and energy dispersive X-ray spectroscopy. The enterolith showed a multilayered structure with fatty acid calcium and magnesium phosphate. The amount of calcium, magnesium, and phosphate decreased after they were immersed in a citric acid solution, suggesting a potential contribution of acidic aqueous solution to elute inorganic substances contained in calcified enteroliths. This is the first study to investigate the in vitro dissolubility of calcified enteroliths induced by citric acid solution.http://dx.doi.org/10.1155/2017/2951547
collection DOAJ
language English
format Article
sources DOAJ
author Masaya Iwamuro
Haruo Urata
Sakiko Hiraoka
Masayasu Ohmori
Yoshitaka Kondo
Yoshiro Kawahara
Hiroyuki Okada
spellingShingle Masaya Iwamuro
Haruo Urata
Sakiko Hiraoka
Masayasu Ohmori
Yoshitaka Kondo
Yoshiro Kawahara
Hiroyuki Okada
A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid
Case Reports in Gastrointestinal Medicine
author_facet Masaya Iwamuro
Haruo Urata
Sakiko Hiraoka
Masayasu Ohmori
Yoshitaka Kondo
Yoshiro Kawahara
Hiroyuki Okada
author_sort Masaya Iwamuro
title A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid
title_short A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid
title_full A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid
title_fullStr A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid
title_full_unstemmed A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid
title_sort calcium enterolith in a patient with crohn’s disease and its in vitro dissolubility in citric acid
publisher Hindawi Limited
series Case Reports in Gastrointestinal Medicine
issn 2090-6528
2090-6536
publishDate 2017-01-01
description The microstructure and dissolubility of a calcified enterolith and enterolith pieces removed from a 26-year-old Japanese woman with Crohn’s disease were analyzed using scanning electron microscopy and energy dispersive X-ray spectroscopy. The enterolith showed a multilayered structure with fatty acid calcium and magnesium phosphate. The amount of calcium, magnesium, and phosphate decreased after they were immersed in a citric acid solution, suggesting a potential contribution of acidic aqueous solution to elute inorganic substances contained in calcified enteroliths. This is the first study to investigate the in vitro dissolubility of calcified enteroliths induced by citric acid solution.
url http://dx.doi.org/10.1155/2017/2951547
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