Tyrosine phosphatases such as SHP-2 act in a balance with Src-family kinases in stabilization of postsynaptic clusters of acetylcholine receptors
<p>Abstract</p> <p>Background</p> <p>Development of neural networks requires that synapses are formed, eliminated and stabilized. At the neuromuscular junction (NMJ), agrin/MuSK signaling, by triggering downstream pathways, causes clustering and phosphorylation of posts...
Main Authors: | Rüegg Markus A, Lin Shuo, Sadasivam Gayathri, Willmann Raffaella, Camilleri Alain A, Gesemann Matthias, Fuhrer Christian |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-07-01
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Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/8/46 |
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