A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells

A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells

Abstract Background Exosomes and other extracellular vesicles (EVs) have emerged as an important mechanism of cell-to-cell communication. However, previous studies either did not fully resolve what genetic materials were shuttled by exosomes or only focused on a specific set of miRNAs and mRNAs. A m...

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Bibliographic Details
Main Authors: Jialiang Yang, Jacob Hagen, Kalyani V. Guntur, Kimaada Allette, Sarah Schuyler, Jyoti Ranjan, Francesca Petralia, Stephane Gesta, Robert Sebra, Milind Mahajan, Bin Zhang, Jun Zhu, Sander Houten, Andrew Kasarskis, Vivek K. Vishnudas, Viatcheslav R. Akmaev, Rangaprasad Sarangarajan, Niven R. Narain, Eric E. Schadt, Carmen A. Argmann, Zhidong Tu
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Genomics
Subjects:
Extracellular RNA (exRNA)
Exosome
Cell-to-cell communication
RNA-seq
Macrophages
Adipocytes
Online Access:http://link.springer.com/article/10.1186/s12864-017-4359-1

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