Resistance to early-life stress in mice: effects of genetic background and stress duration

Early-life stress can induce marked behavioural and physiological impairments in adulthood including cognitive deficits, depression, anxiety and gastrointestinal dysfunction. Although robust rat models of early-life stress exist there are few established effective paradigms in the mouse. Genetic bac...

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Bibliographic Details
Main Authors: Helene M. Savignac, Timothy G. Dinan, John F Cryan
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2011.00013/full